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Evaluation of gene delivery strategies to efficiently overexpress functional HLA-G on human bone marrow stromal cells
Mesenchymal stromal cells (MSC) constitutively express low levels of human leukocyte antigen-G (HLA-G), which has been shown to contribute to their immunomodulatory and anti-inflammatory properties. Here, we hypothesized that overexpression of HLA-G on bone marrow-derived MSC would improve their imm...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4178537/ https://www.ncbi.nlm.nih.gov/pubmed/25279386 http://dx.doi.org/10.1038/mtm.2014.41 |