Evaluation of gene delivery strategies to efficiently overexpress functional HLA-G on human bone marrow stromal cells

Mesenchymal stromal cells (MSC) constitutively express low levels of human leukocyte antigen-G (HLA-G), which has been shown to contribute to their immunomodulatory and anti-inflammatory properties. Here, we hypothesized that overexpression of HLA-G on bone marrow-derived MSC would improve their imm...

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Detalles Bibliográficos
Autores principales: Boura, Joana S, Vance, Melisa, Yin, Weihong, Madeira, Catarina, Lobato da Silva, Cláudia, Porada, Christopher D, Almeida-Porada, Graça
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4178537/
https://www.ncbi.nlm.nih.gov/pubmed/25279386
http://dx.doi.org/10.1038/mtm.2014.41

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