Impact of HLA Selection Pressure on HIV Fitness at a Population Level in Mexico and Barbados

Previous studies have demonstrated that effective cytotoxic T lymphocyte (CTL) responses drive the selection of escape mutations that reduce viral replication capacity (VRC). Escape mutations, including those with reduced VRC, can be transmitted and accumulate in a population. Here we compared two a...

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Detalles Bibliográficos
Autores principales: Juarez-Molina, Claudia I., Payne, Rebecca, Soto-Nava, Maribel, Avila-Rios, Santiago, Valenzuela-Ponce, Humberto, Adland, Emily, Leitman, Ellen, Brener, Jacqui, Muenchhoff, Maximilian, Branch, Songee, Landis, Clive, Reyes-Teran, Gustavo, Goulder, Philip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2014
Materias:
Pathogenesis and Immunity
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4178877/
https://www.ncbi.nlm.nih.gov/pubmed/25008926
http://dx.doi.org/10.1128/JVI.01162-14

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4178877/
https://www.ncbi.nlm.nih.gov/pubmed/25008926
http://dx.doi.org/10.1128/JVI.01162-14

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