Host Factors That Interact with the Pestivirus N-Terminal Protease, N(pro), Are Components of the Ribonucleoprotein Complex

The viral N-terminal protease N(pro) of pestiviruses counteracts cellular antiviral defenses through inhibition of IRF3. Here we used mass spectrometry to identify a new role for N(pro) through its interaction with over 55 associated proteins, mainly ribosomal proteins and ribonucleoproteins, includ...

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Detalles Bibliográficos
Autores principales: Jefferson, Matthew, Donaszi-Ivanov, Andras, Pollen, Sean, Dalmay, Tamas, Saalbach, Gerhard, Powell, Penny P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2014
Materias:
Virus-Cell Interactions
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4178888/
https://www.ncbi.nlm.nih.gov/pubmed/24965446
http://dx.doi.org/10.1128/JVI.00984-14

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4178888/
https://www.ncbi.nlm.nih.gov/pubmed/24965446
http://dx.doi.org/10.1128/JVI.00984-14

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