Structure–activity analysis of a CFTR channel potentiator: Distinct molecular parts underlie dual gating effects

The cystic fibrosis (CF) transmembrane conductance regulator (CFTR) is a member of the ATP-binding cassette transporter superfamily that functions as an epithelial chloride channel. Gating of the CFTR ion conduction pore involves a conserved irreversible cyclic mechanism driven by ATP binding and hy...

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Detalles Bibliográficos
Autores principales: Csanády, László, Töröcsik, Beáta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2014
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4178936/
https://www.ncbi.nlm.nih.gov/pubmed/25267914
http://dx.doi.org/10.1085/jgp.201411246

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4178936/
https://www.ncbi.nlm.nih.gov/pubmed/25267914
http://dx.doi.org/10.1085/jgp.201411246

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