Voltage-dependent regulation of Ca(V)2.2 channels by G(q)-coupled receptor is facilitated by membrane-localized β subunit

G protein–coupled receptors (GPCRs) signal through molecular messengers, such as Gβγ, Ca(2+), and phosphatidylinositol 4,5-bisphosphate (PIP(2)), to modulate N-type voltage-gated Ca(2+) (Ca(V)2.2) channels, playing a crucial role in regulating synaptic transmission. However, the cellular pathways th...

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Detalles Bibliográficos
Autores principales: Keum, Dongil, Baek, Christina, Kim, Dong-Il, Kweon, Hae-Jin, Suh, Byung-Chang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2014
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4178937/
https://www.ncbi.nlm.nih.gov/pubmed/25225550
http://dx.doi.org/10.1085/jgp.201411245

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4178937/
https://www.ncbi.nlm.nih.gov/pubmed/25225550
http://dx.doi.org/10.1085/jgp.201411245

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