Intersubunit conformational changes mediate epithelial sodium channel gating

The epithelial Na(+) channel (ENaC) functions as a pathway for Na(+) absorption in the kidney and lung, where it is crucial for Na(+) homeostasis and blood pressure regulation. However, the basic mechanisms that control ENaC gating are poorly understood. Here we define a role in gating for residues...

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Detalles Bibliográficos
Autores principales: Collier, Daniel M., Tomkovicz, Vivian R., Peterson, Zerubbabel J., Benson, Christopher J., Snyder, Peter M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2014
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4178938/
https://www.ncbi.nlm.nih.gov/pubmed/25225551
http://dx.doi.org/10.1085/jgp.201411208

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4178938/
https://www.ncbi.nlm.nih.gov/pubmed/25225551
http://dx.doi.org/10.1085/jgp.201411208

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