DNA methylation dynamics of the human preimplantation embryo

In mammals, cytosine methylation is predominantly restricted to CpG dinucleotides and stably distributed across the genome, with local, cell type-specific regulation directed by DNA binding factors(1-3). This comparatively static landscape dramatically contrasts the events of fertilization, where th...

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Detalles Bibliográficos
Autores principales: Smith, Zachary D., Chan, Michelle M., Humm, Kathryn C., Karnik, Rahul, Mekhoubad, Shila, Regev, Aviv, Eggan, Kevin, Meissner, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4178976/
https://www.ncbi.nlm.nih.gov/pubmed/25079558
http://dx.doi.org/10.1038/nature13581

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4178976/
https://www.ncbi.nlm.nih.gov/pubmed/25079558
http://dx.doi.org/10.1038/nature13581

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