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Uremic Toxins Enhance Statin-Induced Cytotoxicity in Differentiated Human Rhabdomyosarcoma Cells

The risk of myopathy and rhabdomyolysis is considerably increased in statin users with end-stage renal failure (ESRF). Uremic toxins, which accumulate in patients with ESRF, exert cytotoxic effects that are mediated by various mechanisms. Therefore, accumulation of uremic toxins might increase stati...

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Detalles Bibliográficos
Autores principales: Uchiyama, Hitoshi, Tsujimoto, Masayuki, Shinmoto, Tadakazu, Ogino, Hitomi, Oda, Tomoko, Yoshida, Takuya, Furukubo, Taku, Izumi, Satoshi, Yamakawa, Tomoyuki, Tachiki, Hidehisa, Minegaki, Tetsuya, Nishiguchi, Kohshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4179151/
https://www.ncbi.nlm.nih.gov/pubmed/25192420
http://dx.doi.org/10.3390/toxins6092612