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Uremic Toxins Enhance Statin-Induced Cytotoxicity in Differentiated Human Rhabdomyosarcoma Cells
The risk of myopathy and rhabdomyolysis is considerably increased in statin users with end-stage renal failure (ESRF). Uremic toxins, which accumulate in patients with ESRF, exert cytotoxic effects that are mediated by various mechanisms. Therefore, accumulation of uremic toxins might increase stati...
Autores principales: | Uchiyama, Hitoshi, Tsujimoto, Masayuki, Shinmoto, Tadakazu, Ogino, Hitomi, Oda, Tomoko, Yoshida, Takuya, Furukubo, Taku, Izumi, Satoshi, Yamakawa, Tomoyuki, Tachiki, Hidehisa, Minegaki, Tetsuya, Nishiguchi, Kohshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4179151/ https://www.ncbi.nlm.nih.gov/pubmed/25192420 http://dx.doi.org/10.3390/toxins6092612 |
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