Toxin ζ Reversible Induces Dormancy and Reduces the UDP-N-Acetylglucosamine Pool as One of the Protective Responses to Cope with Stress

Toxins of the ζ/PezT family, found in the genome of major human pathogens, phosphorylate the peptidoglycan precursor uridine diphosphate-N-acetylglucosamine (UNAG) leading to unreactive UNAG-3P. Transient over-expression of a PezT variant impairs cell wall biosynthesis and triggers autolysis in Esch...

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Detalles Bibliográficos
Autores principales: Tabone, Mariangela, Ayora, Silvia, Alonso, Juan C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4179160/
https://www.ncbi.nlm.nih.gov/pubmed/25238046
http://dx.doi.org/10.3390/toxins6092787

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4179160/
https://www.ncbi.nlm.nih.gov/pubmed/25238046
http://dx.doi.org/10.3390/toxins6092787

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