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When noise makes music: HIV reactivation with transcriptional noise enhancers
Reactivating latent HIV is key to depleting the virus reservoir in AIDS patients. A recent paper has described the rationale for and discovery of a new class of drugs - transcriptional noise enhancers - that can synergize with conventional transcription activators to more effectively reactivate late...
Autores principales: | Tan, Xu, Elledge, Stephen J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4179226/ https://www.ncbi.nlm.nih.gov/pubmed/25276233 http://dx.doi.org/10.1186/s13073-014-0055-9 |
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