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Dynamic Autophosphorylation of Mps1 Kinase Is Required for Faithful Mitotic Progression
The spindle assembly checkpoint (SAC) is a surveillance mechanism monitoring cell cycle progression, thus ensuring accurate chromosome segregation. The conserved mitotic kinase Mps1 is a key component of the SAC. The human Mps1 exhibits comprehensive phosphorylation during mitosis. However, the rela...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4179234/ https://www.ncbi.nlm.nih.gov/pubmed/25265012 http://dx.doi.org/10.1371/journal.pone.0104723 |