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Genome-Wide Investigation of DNA Methylation Marks Associated with FV Leiden Mutation

In order to investigate whether DNA methylation marks could contribute to the incomplete penetrance of the FV Leiden mutation, a major genetic risk factor for venous thrombosis (VT), we measured genome-wide DNA methylation levels in peripheral blood samples of 98 VT patients carrying the mutation an...

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Detalles Bibliográficos
Autores principales: Aïssi, Dylan, Dennis, Jessica, Ladouceur, Martin, Truong, Vinh, Zwingerman, Nora, Rocanin-Arjo, Ares, Germain, Marine, Paton, Tara A., Morange, Pierre-Emmanuel, Gagnon, France, Trégouët, David-Alexandre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4179266/
https://www.ncbi.nlm.nih.gov/pubmed/25265411
http://dx.doi.org/10.1371/journal.pone.0108087