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A critical role for mTORC1 in erythropoiesis and anemia

Red blood cells (RBC) must coordinate their rate of growth and proliferation with the availability of nutrients, such as iron, but the signaling mechanisms that link the nutritional state to RBC growth are incompletely understood. We performed a screen for cell types that have high levels of signali...

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Detalles Bibliográficos
Autores principales: Knight, Zachary A, Schmidt, Sarah F, Birsoy, Kivanc, Tan, Keith, Friedman, Jeffrey M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4179304/
https://www.ncbi.nlm.nih.gov/pubmed/25201874
http://dx.doi.org/10.7554/eLife.01913