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T-Cell Costimulation Protects Obesity-Induced Adipose Inflammation and Insulin Resistance

A key pathophysiologic role for activated T-cells in mediating adipose inflammation and insulin resistance (IR) has been recently postulated. However, mechanisms underlying their activation are poorly understood. In this study, we demonstrated a previously unrecognized homeostatic role for the costi...

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Detalles Bibliográficos
Autores principales: Zhong, Jixin, Rao, Xiaoquan, Braunstein, Zachary, Taylor, Anne, Narula, Vimal, Hazey, Jeffrey, Mikami, Dean, Needleman, Bradley, Rutsky, Jessica, Sun, Qinghua, Deiuliis, Jeffrey A., Satoskar, Abhay R., Rajagopalan, Sanjay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4179314/
https://www.ncbi.nlm.nih.gov/pubmed/24222350
http://dx.doi.org/10.2337/db13-1094