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T-Cell Costimulation Protects Obesity-Induced Adipose Inflammation and Insulin Resistance
A key pathophysiologic role for activated T-cells in mediating adipose inflammation and insulin resistance (IR) has been recently postulated. However, mechanisms underlying their activation are poorly understood. In this study, we demonstrated a previously unrecognized homeostatic role for the costi...
Autores principales: | Zhong, Jixin, Rao, Xiaoquan, Braunstein, Zachary, Taylor, Anne, Narula, Vimal, Hazey, Jeffrey, Mikami, Dean, Needleman, Bradley, Rutsky, Jessica, Sun, Qinghua, Deiuliis, Jeffrey A., Satoskar, Abhay R., Rajagopalan, Sanjay |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4179314/ https://www.ncbi.nlm.nih.gov/pubmed/24222350 http://dx.doi.org/10.2337/db13-1094 |
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