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The dynamics of signal amplification by macromolecular assemblies for the control of chromosome segregation
The control of chromosome segregation relies on the spindle assembly checkpoint (SAC), a complex regulatory system that ensures the high fidelity of chromosome segregation in higher organisms by delaying the onset of anaphase until each chromosome is properly bi-oriented on the mitotic spindle. Cent...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4179342/ https://www.ncbi.nlm.nih.gov/pubmed/25324779 http://dx.doi.org/10.3389/fphys.2014.00368 |