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Interpreting trial results following use of different intention-to-treat approaches for preventing attrition bias: a meta-epidemiological study protocol

INTRODUCTION: When participants drop out of randomised clinical trials, as frequently happens, the intention-to-treat (ITT) principle does not apply, potentially leading to attrition bias. Data lost from patient dropout/lack of follow-up are statistically addressed by imputing, a procedure prone to...

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Detalles Bibliográficos
Autores principales: Dossing, Anna, Tarp, Simon, Furst, Daniel E, Gluud, Christian, Beyene, Joseph, Hansen, Bjarke B, Bliddal, Henning, Christensen, Robin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4179424/
https://www.ncbi.nlm.nih.gov/pubmed/25260368
http://dx.doi.org/10.1136/bmjopen-2014-005297