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Production of recombinant human proinsulin in the milk of transgenic mice

There is a steady increasing demand for insulin worldwide. Current insulin manufacturing capacities can barely meet this increasing demand. The purpose of this study was to test the feasibility of producing human proinsulin in the milk of transgenic animals. Four lines of transgenic mice harboring a...

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Detalles Bibliográficos
Autores principales: Qian, Xi, Kraft, Jana, Ni, Yingdong, Zhao, Feng-Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4179469/
https://www.ncbi.nlm.nih.gov/pubmed/25267062
http://dx.doi.org/10.1038/srep06465