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Promiscuous methionyl-tRNA synthetase mediates adaptive mistranslation to protect cells against oxidative stress
Aminoacyl-tRNA synthetases (ARSs) acylate transfer (t)RNAs with amino acids. Charging tRNAs with the right amino acids is the first step in translation; therefore, the accurate and error-free functioning of ARSs is an essential prerequisite for translational fidelity. A recent study found that methi...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4179492/ https://www.ncbi.nlm.nih.gov/pubmed/25097229 http://dx.doi.org/10.1242/jcs.152470 |