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Promiscuous methionyl-tRNA synthetase mediates adaptive mistranslation to protect cells against oxidative stress

Aminoacyl-tRNA synthetases (ARSs) acylate transfer (t)RNAs with amino acids. Charging tRNAs with the right amino acids is the first step in translation; therefore, the accurate and error-free functioning of ARSs is an essential prerequisite for translational fidelity. A recent study found that methi...

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Detalles Bibliográficos
Autores principales: Lee, Jin Young, Kim, Dae Gyu, Kim, Byung-Gyu, Yang, Won Suk, Hong, Jeena, Kang, Taehee, Oh, Young Sun, Kim, Kyung Rok, Han, Byung Woo, Hwang, Byung Joon, Kang, Beom Sik, Kang, Mi-Sun, Kim, Myung-Hee, Kwon, Nam Hoon, Kim, Sunghoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4179492/
https://www.ncbi.nlm.nih.gov/pubmed/25097229
http://dx.doi.org/10.1242/jcs.152470