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Functional Annotation of Putative Regulatory Elements at Cancer Susceptibility Loci
Most cancer-associated genetic variants identified from genome-wide association studies (GWAS) do not obviously change protein structure, leading to the hypothesis that the associations are attributable to regulatory polymorphisms. Translating genetic associations into mechanistic insights can be fa...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Libertas Academica
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4179605/ https://www.ncbi.nlm.nih.gov/pubmed/25288875 http://dx.doi.org/10.4137/CIN.S13789 |