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Functional Annotation of Putative Regulatory Elements at Cancer Susceptibility Loci

Most cancer-associated genetic variants identified from genome-wide association studies (GWAS) do not obviously change protein structure, leading to the hypothesis that the associations are attributable to regulatory polymorphisms. Translating genetic associations into mechanistic insights can be fa...

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Detalles Bibliográficos
Autores principales: Rosse, Stephanie A, Auer, Paul L, Carlson, Christopher S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Libertas Academica 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4179605/
https://www.ncbi.nlm.nih.gov/pubmed/25288875
http://dx.doi.org/10.4137/CIN.S13789