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Application of Ethylcellulose Coating to Hydrophilic Matrices: A Strategy to Modulate Drug Release Profile and Reduce Drug Release Variability

Hydrophilic matrix tablets are commonly used for extended release dosage forms. For low aqueous-solubility drugs, there may be challenges in modulation of release profiles and achieving consistent release in physiological conditions. To evaluate potential formulation strategies, matrix tablets of a...

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Detalles Bibliográficos
Autores principales: Mehta, Raxit Y., Missaghi, Shahrzad, Tiwari, Sandip B., Rajabi-Siahboomi, Ali R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4179654/
https://www.ncbi.nlm.nih.gov/pubmed/24848757
http://dx.doi.org/10.1208/s12249-014-0128-5