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EPO Mediates Neurotrophic, Neuroprotective, Anti-Oxidant, and Anti-Apoptotic Effects via Downregulation of miR-451 and miR-885-5p in SH-SY5Y Neuron-Like Cells

Erythropoietin (EPO) is a neuroprotective cytokine, which has been applied in several animal models presenting neurological disorders. One of the proposed modes of action resulting in neuroprotection is post-transcriptional gene expression regulation. This directly brings to mind microRNAs (miRNAs),...

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Detalles Bibliográficos
Autores principales: Alural, Begum, Duran, Gizem Ayna, Tufekci, Kemal Ugur, Allmer, Jens, Onkal, Zeynep, Tunali, Dogan, Genc, Kursad, Genc, Sermin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4179732/
https://www.ncbi.nlm.nih.gov/pubmed/25324845
http://dx.doi.org/10.3389/fimmu.2014.00475