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Dual tracer evaluation of dynamic changes in intratumoral hypoxic and proliferative states after radiotherapy of human head and neck cancer xenografts using radiolabeled FMISO and FLT

BACKGROUND: Radiotherapy is an important treatment strategy for head and neck cancers. Tumor hypoxia and repopulation adversely affect the radiotherapy outcome. Accordingly, fractionated radiotherapy with dose escalation or altered fractionation schedule is used to prevent hypoxia and repopulation....

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Detalles Bibliográficos
Autores principales: Fatema, Chowdhury Nusrat, Zhao, Songji, Zhao, Yan, Yu, Wenwen, Nishijima, Ken-ichi, Yasuda, Koichi, Kitagawa, Yoshimasa, Tamaki, Nagara, Kuge, Yuji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4179856/
https://www.ncbi.nlm.nih.gov/pubmed/25245041
http://dx.doi.org/10.1186/1471-2407-14-692