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MicroRNA-146a Decreases High Glucose/Thrombin-Induced Endothelial Inflammation by Inhibiting NAPDH Oxidase 4 Expression

Diabetes is associated with hyperglycemia and increased thrombin production. However, it is unknown whether a combination of high glucose and thrombin can modulate the expression of NAPDH oxidase (Nox) subtypes in human aortic endothelial cells (HAECs). Moreover, we investigated the role of a diabet...

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Detalles Bibliográficos
Autores principales: Wang, Huang-Joe, Huang, Yuan-Li, Shih, Ya-Yun, Wu, Hsing-Yu, Peng, Ching-Tien, Lo, Wan-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4179945/
https://www.ncbi.nlm.nih.gov/pubmed/25298619
http://dx.doi.org/10.1155/2014/379537