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MicroRNA-146a Decreases High Glucose/Thrombin-Induced Endothelial Inflammation by Inhibiting NAPDH Oxidase 4 Expression
Diabetes is associated with hyperglycemia and increased thrombin production. However, it is unknown whether a combination of high glucose and thrombin can modulate the expression of NAPDH oxidase (Nox) subtypes in human aortic endothelial cells (HAECs). Moreover, we investigated the role of a diabet...
Autores principales: | Wang, Huang-Joe, Huang, Yuan-Li, Shih, Ya-Yun, Wu, Hsing-Yu, Peng, Ching-Tien, Lo, Wan-Yu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4179945/ https://www.ncbi.nlm.nih.gov/pubmed/25298619 http://dx.doi.org/10.1155/2014/379537 |
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