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Oxidized LDL lipids increase β-amyloid production by SH-SY5Y cells through glutathione depletion and lipid raft formation
Elevated total cholesterol in midlife has been associated with increased risk of dementia in later life. We have previously shown that low-density lipoprotein (LDL) is more oxidized in the plasma of dementia patients, although total cholesterol levels are not different from those of age-matched cont...
Autores principales: | Dias, Irundika H.K., Mistry, Jayna, Fell, Shaun, Reis, Ana, Spickett, Corinne M., Polidori, Maria C., Lip, Gregory Y.H., Griffiths, Helen R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4180009/ https://www.ncbi.nlm.nih.gov/pubmed/25048970 http://dx.doi.org/10.1016/j.freeradbiomed.2014.07.012 |
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