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Defining Differential Genetic Signatures in CXCR4- and the CCR5-Utilizing HIV-1 Co-Linear Sequences

The adaptation of human immunodeficiency virus type-1 (HIV-1) to an array of physiologic niches is advantaged by the plasticity of the viral genome, encoded proteins, and promoter. CXCR4-utilizing (X4) viruses preferentially, but not universally, infect CD4(+) T cells, generating high levels of viru...

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Detalles Bibliográficos
Autores principales: Aiamkitsumrit, Benjamas, Dampier, Will, Martin-Garcia, Julio, Nonnemacher, Michael R., Pirrone, Vanessa, Ivanova, Tatyana, Zhong, Wen, Kilareski, Evelyn, Aldigun, Hazeez, Frantz, Brian, Rimbey, Matthew, Wojno, Adam, Passic, Shendra, Williams, Jean W., Shah, Sonia, Blakey, Brandon, Parikh, Nirzari, Jacobson, Jeffrey M., Moldover, Brian, Wigdahl, Brian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4180074/
https://www.ncbi.nlm.nih.gov/pubmed/25265194
http://dx.doi.org/10.1371/journal.pone.0107389