Cargando…

Defining Differential Genetic Signatures in CXCR4- and the CCR5-Utilizing HIV-1 Co-Linear Sequences

The adaptation of human immunodeficiency virus type-1 (HIV-1) to an array of physiologic niches is advantaged by the plasticity of the viral genome, encoded proteins, and promoter. CXCR4-utilizing (X4) viruses preferentially, but not universally, infect CD4(+) T cells, generating high levels of viru...

Descripción completa

Detalles Bibliográficos
Autores principales:	Aiamkitsumrit, Benjamas, Dampier, Will, Martin-Garcia, Julio, Nonnemacher, Michael R., Pirrone, Vanessa, Ivanova, Tatyana, Zhong, Wen, Kilareski, Evelyn, Aldigun, Hazeez, Frantz, Brian, Rimbey, Matthew, Wojno, Adam, Passic, Shendra, Williams, Jean W., Shah, Sonia, Blakey, Brandon, Parikh, Nirzari, Jacobson, Jeffrey M., Moldover, Brian, Wigdahl, Brian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4180074/ https://www.ncbi.nlm.nih.gov/pubmed/25265194 http://dx.doi.org/10.1371/journal.pone.0107389

Ejemplares similares

HIV-1 Promoter Single Nucleotide Polymorphisms Are Associated with Clinical Disease Severity
por: Nonnemacher, Michael R., et al.
Publicado: (2016)

HIV-1 Genetic Variation Resulting in the Development of New Quasispecies Continues to Be Encountered in the Peripheral Blood of Well-Suppressed Patients
por: Dampier, Will, et al.
Publicado: (2016)

Utilization of HIV-1 envelope V3 to identify X4- and R5-specific Tat and LTR sequence signatures
por: Antell, Gregory C., et al.
Publicado: (2016)

Evidence of Divergent Amino Acid Usage in Comparative Analyses of R5- and X4-Associated HIV-1 Vpr Sequences
por: Antell, Gregory C., et al.
Publicado: (2017)

Effect of μ-opioid agonist DAMGO on surface CXCR4 and HIV-1 replication in TF-1 human bone marrow progenitor cells
por: Strazza, Marianne, et al.
Publicado: (2014)

Application and removal of polyanionic microbicide compounds enhances subsequent infection by HIV-1
por: Pirrone, Vanessa, et al.
Publicado: (2012)

Impact of Tat Genetic Variation on HIV-1 Disease
por: Li, Luna, et al.
Publicado: (2012)

Mitochondrial Haplogroup Influences Motor Function in Long-Term HIV-1-Infected Individuals
por: Azar, Ashley, et al.
Publicado: (2016)

A Styrene-alt-Maleic Acid Copolymer Is an Effective Inhibitor of R5 and X4 Human Immunodeficiency Virus Type 1 Infection
por: Pirrone, Vanessa, et al.
Publicado: (2010)

Functional Studies of CCAAT/Enhancer Binding Protein Site Located Downstream of the Transcriptional Start Site
por: Liu, Yujie, et al.
Publicado: (2017)

Regulation of HIV-1 transcription in cells of the monocyte-macrophage lineage
por: Kilareski, Evelyn M, et al.
Publicado: (2009)

Novel gRNA design pipeline to develop broad-spectrum CRISPR/Cas9 gRNAs for safe targeting of the HIV-1 quasispecies in patients
por: Sullivan, Neil T., et al.
Publicado: (2019)

CCAAT Enhancer Binding Protein and Nuclear Factor of Activated T Cells Regulate HIV-1 LTR via a Novel Conserved Downstream Site in Cells of the Monocyte-Macrophage Lineage
por: Dahiya, Satinder, et al.
Publicado: (2014)

Infection by CXCR4-Tropic Human Immunodeficiency Virus Type 1 Is Inhibited by the Cationic Cell-Penetrating Peptide Derived from HIV-1 Tat
por: Keogan, Shawn, et al.
Publicado: (2012)

HIV-1 Tat Length: Comparative and Functional Considerations
por: Mele, Anthony R., et al.
Publicado: (2020)

Impact of Viral Activators and Epigenetic Regulators on HIV-1 LTRs Containing Naturally Occurring Single Nucleotide Polymorphisms
por: Shah, Sonia, et al.
Publicado: (2015)

Targeting CCR5 as a Component of an HIV-1 Therapeutic Strategy
por: Mohamed, Hager, et al.
Publicado: (2022)

Interaction between Tat and Drugs of Abuse during HIV-1 Infection and Central Nervous System Disease
por: Maubert, Monique E., et al.
Publicado: (2016)

Functional properties of the HIV-1 long terminal repeat containing single-nucleotide polymorphisms in Sp site III and CCAAT/enhancer binding protein site I
por: Shah, Sonia, et al.
Publicado: (2014)

Designing broad-spectrum anti-HIV-1 gRNAs to target patient-derived variants
por: Dampier, Will, et al.
Publicado: (2017)

cAMP Signaling Enhances HIV-1 Long Terminal Repeat (LTR)-directed Transcription and Viral Replication in Bone Marrow Progenitor Cells
por: Banerjee, Anupam, et al.
Publicado: (2017)

Prolonged Morphine Exposure Induces Increased Firm Adhesion in an in Vitro Model of the Blood–Brain Barrier
por: Strazza, Marianne, et al.
Publicado: (2016)

Gene Editing of HIV-1 Co-receptors to Prevent and/or Cure Virus Infection
por: Allen, Alexander G., et al.
Publicado: (2018)

Designing Safer CRISPR/Cas9 Therapeutics for HIV: Defining Factors That Regulate and Technologies Used to Detect Off-Target Editing
por: Sullivan, Neil T., et al.
Publicado: (2020)

Integrated Human Immunodeficiency Virus Type 1 Sequence in J-Lat 10.6
por: Chung, Cheng-Han, et al.
Publicado: (2020)

Computational Design of gRNAs Targeting Genetic Variants Across HIV-1 Subtypes for CRISPR-Mediated Antiviral Therapy
por: Chung, Cheng-Han, et al.
Publicado: (2021)

Cellular phenotype impacts human immunodeficiency virus type 1 viral protein R subcellular localization
por: Ferrucci, Adriano, et al.
Publicado: (2011)

Extracellular HIV-1 Tat Mediates Increased Glutamate in the CNS Leading to Onset of Senescence and Progression of HAND
por: Marino, Jamie, et al.
Publicado: (2020)

Off-Target Analysis in Gene Editing and Applications for Clinical Translation of CRISPR/Cas9 in HIV-1 Therapy
por: Atkins, Andrew, et al.
Publicado: (2021)

Immunomodulatory Effects of Non-Thermal Plasma in a Model for Latent HIV-1 Infection: Implications for an HIV-1-Specific Immunotherapy
por: Mohamed, Hager, et al.
Publicado: (2023)

Opinion: Inhibition of Blood-Brain Barrier Repair as a Mechanism in HIV-1 Disease
por: Maubert, Monique E., et al.
Publicado: (2017)

584. Investigation of the Association Between Neurocognitive Function and Depression in HIV Infection
por: Mumford, Brigid, et al.
Publicado: (2018)

Assessment of anti-HIV-1 guide RNA efficacy in cells containing the viral target sequence, corresponding gRNA, and CRISPR/Cas9
por: Allen, Alexander G., et al.
Publicado: (2023)

Roles of neuropathology-associated reactive astrocytes: a systematic review
por: Lawrence, Jill M., et al.
Publicado: (2023)

Safe CRISPR-Cas9 Inhibition of HIV-1 with High Specificity and Broad-Spectrum Activity by Targeting LTR NF-κB Binding Sites
por: Chung, Cheng-Han, et al.
Publicado: (2020)

Biomarkers of HIV Susceptibility and Disease Progression()
por: Pirrone, Vanessa, et al.
Publicado: (2014)

Chronic Low Dose Morphine Does Not Alter Two In Vitro BBB Models
por: Marino, Jamie, et al.
Publicado: (2022)

High-Level Production, Solubilization and Purification of Synthetic Human GPCR Chemokine Receptors CCR5, CCR3, CXCR4 and CX3CR1
por: Ren, Hui, et al.
Publicado: (2009)

CCR5 and CXCR4 antagonist and agonist binding sites
por: Teintze, Martin, et al.
Publicado: (2006)

CCR3, CCR4, CCR5, and CXCR3 expression in peripheral blood CD4+ lymphocytes in gastric cancer patients
por: Andalib, Alireza, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_sk24sansl3bjuqggratamio6d7