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Inhibition of phosphodiesterase10A attenuates morphine-induced conditioned place preference
BACKGROUND: Phosphodiesterase (PDE) 10A is selectively expressed in medium spiny neurons of the striatum. Nucleus accumbens (NAc) is a key region that mediates drug reward and addiction-related behaviors. To investigate the potential role of PDE10A in the reinforcement properties of morphine, we tes...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4180334/ https://www.ncbi.nlm.nih.gov/pubmed/25252626 http://dx.doi.org/10.1186/s13041-014-0070-1 |