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Inhibition of phosphodiesterase10A attenuates morphine-induced conditioned place preference

BACKGROUND: Phosphodiesterase (PDE) 10A is selectively expressed in medium spiny neurons of the striatum. Nucleus accumbens (NAc) is a key region that mediates drug reward and addiction-related behaviors. To investigate the potential role of PDE10A in the reinforcement properties of morphine, we tes...

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Detalles Bibliográficos
Autores principales:	Mu, Ying, Ren, Zhaoxiang, Jia, Jia, Gao, Bo, Zheng, Longtai, Wang, Guanghui, Friedman, Eitan, Zhen, Xuechu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4180334/ https://www.ncbi.nlm.nih.gov/pubmed/25252626 http://dx.doi.org/10.1186/s13041-014-0070-1

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