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Implication of the cause of differences in 3D structures of proteins with high sequence identity based on analyses of amino acid sequences and 3D structures

BACKGROUND: Proteins that share a high sequence homology while exhibiting drastically different 3D structures are investigated in this study. Recently, artificial proteins related to the sequences of the GA and IgG binding GB domains of human serum albumin have been designed. These artificial protei...

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Detalles Bibliográficos
Autores principales: Matsuoka, Masanari, Sugita, Masatake, Kikuchi, Takeshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4180342/
https://www.ncbi.nlm.nih.gov/pubmed/25231773
http://dx.doi.org/10.1186/1756-0500-7-654