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Alterations of the Ca(2+) signaling pathway in pancreatic beta-cells isolated from db/db mice

Upon glucose elevation, pancreatic beta-cells secrete insulin in a Ca(2+)-dependent manner. In diabetic animal models, different aspects of the calcium signaling pathway in beta-cells are altered, but there is no consensus regarding their relative contributions to the development of beta-cell dysfun...

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Detalles Bibliográficos
Autores principales:	Liang, Kuo, Du, Wen, Lu, Jingze, Li, Fei, Yang, Lu, Xue, Yanhong, Hille, Bertil, Chen, Liangyi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Higher Education Press 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4180459/ https://www.ncbi.nlm.nih.gov/pubmed/25053525 http://dx.doi.org/10.1007/s13238-014-0075-7

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