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Getting out of a wheelchair: an uncommon insertion mutation in exon 19 of EGFR responsive to erlotinib

BACKGROUND: Most patients with non-small cell lung cancer (NSCLC) present with advanced disease and have poor long-term prognosis. Advanced NSCLC that contains characteristic mutations in epidermal growth factor receptor (EGFR) are highly sensitive to EGFR tyrosine kinase inhibitors (TKIs). EGFR exo...

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Detalles Bibliográficos
Autores principales: Agbarya, Abed, Melamed-Frank, Meira, Kaidar-Person, Orit, Goldberg-Cohen, Ilana, Nasrallah, Haitam, Wollner, Mira, Bar, Jair, Rennert, Gad, Lejbkowicz, Flavio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4180504/
https://www.ncbi.nlm.nih.gov/pubmed/25279299
http://dx.doi.org/10.1186/2193-1801-3-507