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Systematic evaluation of quantotypic peptides for targeted analysis of the human kinome

In targeted proteomics it is critical that peptides are not only proteotypic, but also accurately represent the level of the protein (quantotypic). Numerous approaches are used to identify proteotypic peptides, but quantotypic properties are rarely assessed. Here, we show that measuring ratios of pr...

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Detalles Bibliográficos
Autores principales: Worboys, Jonathan D., Sinclair, John, Yuan, Yinyin, Jørgensen, Claus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4180722/
https://www.ncbi.nlm.nih.gov/pubmed/25152083
http://dx.doi.org/10.1038/nmeth.3072