Cryptic Determinant of α4β7 Binding in the V2 Loop of HIV-1 gp120

The peptide segment of the second variable loop of HIV-1 spanning positions 166–181 harbors two functionally important sites. The first, spanning positions 179–181, engages the human α4β7 integrin receptor which is involved in T-cell gut-homing and may play a role in human immunodeficiency virus (HI...

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Detalles Bibliográficos
Autores principales: Tassaneetrithep, Boonrat, Tivon, Doreen, Swetnam, James, Karasavvas, Nicos, Michael, Nelson L., Kim, Jerome H., Marovich, Mary, Cardozo, Timothy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4180765/
https://www.ncbi.nlm.nih.gov/pubmed/25265384
http://dx.doi.org/10.1371/journal.pone.0108446

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4180765/
https://www.ncbi.nlm.nih.gov/pubmed/25265384
http://dx.doi.org/10.1371/journal.pone.0108446

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