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Cryptic Determinant of α4β7 Binding in the V2 Loop of HIV-1 gp120
The peptide segment of the second variable loop of HIV-1 spanning positions 166–181 harbors two functionally important sites. The first, spanning positions 179–181, engages the human α4β7 integrin receptor which is involved in T-cell gut-homing and may play a role in human immunodeficiency virus (HI...
Autores principales: | Tassaneetrithep, Boonrat, Tivon, Doreen, Swetnam, James, Karasavvas, Nicos, Michael, Nelson L., Kim, Jerome H., Marovich, Mary, Cardozo, Timothy |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4180765/ https://www.ncbi.nlm.nih.gov/pubmed/25265384 http://dx.doi.org/10.1371/journal.pone.0108446 |
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