DPP4 inhibition attenuates filtration barrier injury and oxidant stress in the Zucker obese rat

OBJECTIVE: Obesity-related glomerulopathy is characterized initially by glomerular hyperfiltration with hypertrophy and then development of proteinuria. Putative mechanisms include endothelial dysfunction and filtration barrier injury due to oxidant stress and immune activation. There has been recen...

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Detalles Bibliográficos
Autores principales: Nistala, Ravi, Habibi, Javad, Aroor, Annayya, Sowers, James R, Hayden, Melvin R, Meuth, Alex, Knight, William, Hancock, Tamara, Klein, Thomas, DeMarco, Vincent G, Whaley-Connell, Adam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4180797/
https://www.ncbi.nlm.nih.gov/pubmed/24995775
http://dx.doi.org/10.1002/oby.20833

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4180797/
https://www.ncbi.nlm.nih.gov/pubmed/24995775
http://dx.doi.org/10.1002/oby.20833

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