Simple knockout by electroporation of engineered endonucleases into intact rat embryos

Engineered endonucleases, such as zinc-finger nucleases (ZFNs), transcription activator-like effector nucleases (TALENs), and the clustered regularly interspaced short palindromic repeat (CRISPR)/CRISPR-associated (Cas) system, provide a powerful approach for genome editing in animals. However, the...

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Detalles Bibliográficos
Autores principales: Kaneko, Takehito, Sakuma, Tetsushi, Yamamoto, Takashi, Mashimo, Tomoji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4180828/
https://www.ncbi.nlm.nih.gov/pubmed/25269785
http://dx.doi.org/10.1038/srep06382

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4180828/
https://www.ncbi.nlm.nih.gov/pubmed/25269785
http://dx.doi.org/10.1038/srep06382

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