Sensitive methods for detection of the S768R substitution in exon 18 of the DDR2 gene in patients with central nervous system metastases of non-small cell lung cancer

Discoidin death receptor 2 (DDR2) receptor belongs to a DDR family that shows a tyrosine kinase activity. The somatic mutations in DDR2 gene, reported in non-small cell lung cancer (NSCLC), are involved in up-regulation of cells’ migration, proliferation and survival. A S768R substitution in DDR2 ge...

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Detalles Bibliográficos
Autores principales: Nicoś, Marcin, Powrózek, Tomasz, Krawczyk, Paweł, Jarosz, Bożena, Pająk, Beata, Sawicki, Marek, Kucharczyk, Krzysztof, Trojanowski, Tomasz, Milanowski, Janusz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2014
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4180903/
https://www.ncbi.nlm.nih.gov/pubmed/25173530
http://dx.doi.org/10.1007/s12032-014-0176-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4180903/
https://www.ncbi.nlm.nih.gov/pubmed/25173530
http://dx.doi.org/10.1007/s12032-014-0176-4

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