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Distinct structural transitions of chromatin topological domains correlate with coordinated hormone-induced gene regulation

The human genome is segmented into topologically associating domains (TADs), but the role of this conserved organization during transient changes in gene expression is not known. Here we describe the distribution of progestin-induced chromatin modifications and changes in transcriptional activity ov...

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Detalles Bibliográficos
Autores principales: Le Dily, François, Baù, Davide, Pohl, Andy, Vicent, Guillermo P., Serra, François, Soronellas, Daniel, Castellano, Giancarlo, Wright, Roni H.G., Ballare, Cecilia, Filion, Guillaume, Marti-Renom, Marc A., Beato, Miguel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4180976/
https://www.ncbi.nlm.nih.gov/pubmed/25274727
http://dx.doi.org/10.1101/gad.241422.114