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Distinct structural transitions of chromatin topological domains correlate with coordinated hormone-induced gene regulation
The human genome is segmented into topologically associating domains (TADs), but the role of this conserved organization during transient changes in gene expression is not known. Here we describe the distribution of progestin-induced chromatin modifications and changes in transcriptional activity ov...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4180976/ https://www.ncbi.nlm.nih.gov/pubmed/25274727 http://dx.doi.org/10.1101/gad.241422.114 |