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The Prox1–Vegfr3 feedback loop maintains the identity and the number of lymphatic endothelial cell progenitors

The mammalian lymphatic vasculature is important for returning fluids from the extracellular tissue milieu back to the blood circulation. We showed previously that Prox1 dosage is important for the development of the mammalian lymphatic vasculature. The lack of Prox1 activity results in the complete...

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Detalles Bibliográficos
Autores principales: Srinivasan, R. Sathish, Escobedo, Noelia, Yang, Ying, Interiano, Ashley, Dillard, Miriam E., Finkelstein, David, Mukatira, Suraj, Gil, Hyea Jin, Nurmi, Harri, Alitalo, Kari, Oliver, Guillermo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4180978/
https://www.ncbi.nlm.nih.gov/pubmed/25274728
http://dx.doi.org/10.1101/gad.216226.113