Effects of Isoxazolo-Pyridinone 7e, a Potent Activator of the Nurr1 Signaling Pathway, on Experimental Autoimmune Encephalomyelitis in Mice

Multiple sclerosis (MS) is an autoimmune chronic disease of the central nervous system (CNS) characterized by immune-mediated inflammation, demyelination and subsequent axonal damage. Gene expression profiling showed that Nurr1, an orphan nuclear receptor, is down-regulated in peripheral blood monon...

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Detalles Bibliográficos
Autores principales: Montarolo, Francesca, Raffaele, Chiara, Perga, Simona, Martire, Serena, Finardi, Annamaria, Furlan, Roberto, Hintermann, Samuel, Bertolotto, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4181297/
https://www.ncbi.nlm.nih.gov/pubmed/25265488
http://dx.doi.org/10.1371/journal.pone.0108791

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4181297/
https://www.ncbi.nlm.nih.gov/pubmed/25265488
http://dx.doi.org/10.1371/journal.pone.0108791

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