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HDAC4 blocks autophagy to trigger podocyte injury: non-epigenetic action in diabetic nephropathy

Histone deacetylases (HDACs) have been implicated in the pathogenesis of kidney diseases including diabetic nephropathy (DN); however, the underlying mechanism is poorly understood. In this issue, Wang et. al. have unraveled the changes in expression of various HDACs in DN and demonstrated that HDAC...

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Detalles Bibliográficos
Autores principales: Wei, Qingqing, Dong, Zheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4181378/
https://www.ncbi.nlm.nih.gov/pubmed/25265947
http://dx.doi.org/10.1038/ki.2014.142