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Non-neural tyrosine hydroxylase, via modulation of endocrine pancreatic precursors, is required for normal development of beta cells in the mouse pancreas

AIMS/HYPOTHESIS: Apart from transcription factors, little is known about the molecules that modulate the proliferation and differentiation of pancreatic endocrine cells. The early expression of tyrosine hydroxylase (TH) in a subset of glucagon(+) cells led us to investigate whether catecholamines ha...

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Detalles Bibliográficos
Autores principales: Vázquez, Patricia, Robles, Ana M., de Pablo, Flora, Hernández-Sánchez, Catalina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4181516/
https://www.ncbi.nlm.nih.gov/pubmed/25082160
http://dx.doi.org/10.1007/s00125-014-3341-6