Synthesis and antibacterial activities of acylide derivatives bearing an aryl-tetrazolyl chain

Seventeen acylides bearing an aryl-tetrazolyl alkyl-substituted side chain were synthesized, starting from clarithromycin, via several reactions including hydrolysis, acetylating, esterification, carbamylation, and Michael addition. The structures of all new compounds were confirmed by (1)H nuclear...

Descripción completa

Detalles Bibliográficos
Autores principales: Shan, Ling-Xing, Sun, Ping-Hua, Guo, Bao-Qin, Xu, Xing-Jun, Li, Zhi-Qiang, Sun, Jia-Zhi, Zhou, Shu-Feng, Chen, Wei-Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4181547/
https://www.ncbi.nlm.nih.gov/pubmed/25284984
http://dx.doi.org/10.2147/DDDT.S65673

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4181547/
https://www.ncbi.nlm.nih.gov/pubmed/25284984
http://dx.doi.org/10.2147/DDDT.S65673

Ejemplares similares