Interferon-γ and celecoxib inhibit lung-tumor growth through modulating M2/M1 macrophage ratio in the tumor microenvironment

Tumor-associated macrophages play an important role in tumor growth and progression. These macrophages are heterogeneous with diverse functions, eg, M1 macrophages inhibit tumor growth, whereas M2 macrophages promote tumor growth. In this study, we found that IFNγ and/or celecoxib (cyclooxygenase-2...

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Detalles Bibliográficos
Autores principales: Ren, Fuqiang, Fan, Mingyu, Mei, Jiandong, Wu, Yongqiang, Liu, Chengwu, Pu, Qiang, You, Zongbing, Liu, Lunxu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4181549/
https://www.ncbi.nlm.nih.gov/pubmed/25284985
http://dx.doi.org/10.2147/DDDT.S66302

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4181549/
https://www.ncbi.nlm.nih.gov/pubmed/25284985
http://dx.doi.org/10.2147/DDDT.S66302

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