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Provisional in-silico biopharmaceutics classification (BCS) to guide oral drug product development

The main objective of this work was to investigate in-silico predictions of physicochemical properties, in order to guide oral drug development by provisional biopharmaceutics classification system (BCS). Four in-silico methods were used to estimate LogP: group contribution (CLogP) using two differe...

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Detalles Bibliográficos
Autores principales: Wolk, Omri, Agbaria, Riad, Dahan, Arik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4181551/
https://www.ncbi.nlm.nih.gov/pubmed/25284986
http://dx.doi.org/10.2147/DDDT.S68909