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Purification of the Cystic Fibrosis Transmembrane Conductance Regulator Protein Expressed in Saccharomyces cerevisiae

Defects in the cystic fibrosis transmembrane conductance regulator (CFTR) protein cause cystic fibrosis (CF), an autosomal recessive disease that currently limits the average life expectancy of sufferers to <40 years of age. The development of novel drug molecules to restore the activity of CFTR...

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Detalles Bibliográficos
Autores principales: Pollock, Naomi, Cant, Natasha, Rimington, Tracy, Ford, Robert C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MyJove Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4181556/
https://www.ncbi.nlm.nih.gov/pubmed/24893839
http://dx.doi.org/10.3791/51447